T508-0003 Screening compound: N~8~-(3-morpholinopropyl)-5-oxo-7-phenyl-1,2,3,5-tetrahydro-8-indolizinecarboxamide

T508-0003 Screening compound: N~8~-(3-morpholinopropyl)-5-oxo-7-phenyl-1,2,3,5-tetrahydro-8-indolizinecarboxamide
T508-0003 Screening compound: N~8~-(3-morpholinopropyl)-5-oxo-7-phenyl-1,2,3,5-tetrahydro-8-indolizinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T508-0003
N~8~-(3-morpholinopropyl)-5-oxo-7-phenyl-1,2,3,5-tetrahydro-8-indolizinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T508-0003

Molecular Formula

C22H27N3O3 (C22 H27 N3 O3)

Compound Name

N~8~-(3-morpholinopropyl)-5-oxo-7-phenyl-1,2,3,5-tetrahydro-8-indolizinecarboxamide

IUPAC name

N-[3-(morpholin-4-yl)propyl]-5-oxo-7-phenyl-1235-tetrahydroindolizine-8-carboxamide

SMILES

O=C(C(C(c1ccccc1)=C1)=C(CCC2)N2C1=O)NCCCN1CCOCC1

InChI

InChI=1S/C22H27N3O3/c26-20-16-18(17-6-2-1-3-7-17)21(19-8-4-11-25(19)20)22(27)23-9-5-10-24-12-14-28-15-13-24/h1-3,6-7,16H,4-5,8-15H2,(H,23,27)

InChI Key

YXSDWKAFKJMCIO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31974098

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.997

Distribution Coefficient, logD

0.608

Water Solubility, LogSw

-1.88

Polar Surface Area

53.240

Acid Dissociation Constant (pKa)

12.49

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.45

T508-0003 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T508-0003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T508-0003?
Check Price and Availability of T508-0003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T508-0003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T508-0003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T508-0003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T508-0003 available by request