T508-0116 Screening compound: N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

T508-0116 Screening compound: N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1,2,3,5-tetrahydroindolizine-8-carboxamide
T508-0116 Screening compound: N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1,2,3,5-tetrahydroindolizine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T508-0116
N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T508-0116

Molecular Formula

C24H24N2O3 (C24 H24 N2 O3)

Compound Name

N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

IUPAC name

N-[(2-ethoxyphenyl)methyl]-5-oxo-7-phenyl-1235-tetrahydroindolizine-8-carboxamide

SMILES

CCOc1c(CNC(C(C(c2ccccc2)=C2)=C(CCC3)N3C2=O)=O)cccc1

InChI

InChI=1S/C24H24N2O3/c1-2-29-21-13-7-6-11-18(21)16-25-24(28)23-19(17-9-4-3-5-10-17)15-22(27)26-14-8-12-20(23)26/h3-7,9-11,13,15H,2,8,12,14,16H2,1H3,(H,25,28)

InChI Key

MSIJDIXLVOKERC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31973357

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.411

Distribution Coefficient, logD

3.409

Water Solubility, LogSw

-3.59

Polar Surface Area

48.718

Acid Dissociation Constant (pKa)

9.98

Base Dissociation Constant (pKb)

-1.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

T508-0116 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T508-0116 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T508-0116?
Check Price and Availability of T508-0116, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T508-0116 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T508-0116
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T508-0116
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T508-0116 available by request