T655-0027 Screening compound: 1-[4-(5-isopropyl-1,3,4-oxadiazol-2-yl)-8-oxa-2-azaspiro[4.5]dec-2-yl]-3-methyl-1-butanone

T655-0027 Screening compound: 1-[4-(5-isopropyl-1,3,4-oxadiazol-2-yl)-8-oxa-2-azaspiro[4.5]dec-2-yl]-3-methyl-1-butanone
T655-0027 Screening compound: 1-[4-(5-isopropyl-1,3,4-oxadiazol-2-yl)-8-oxa-2-azaspiro[4.5]dec-2-yl]-3-methyl-1-butanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T655-0027
1-[4-(5-isopropyl-1,3,4-oxadiazol-2-yl)-8-oxa-2-azaspiro[4.5]dec-2-yl]-3-methyl-1-butanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T655-0027

Molecular Formula

C18H29N3O3 (C18 H29 N3 O3)

Compound Name

1-[4-(5-isopropyl-1,3,4-oxadiazol-2-yl)-8-oxa-2-azaspiro[4.5]dec-2-yl]-3-methyl-1-butanone

IUPAC name

3-methyl-1-{4-[5-(propan-2-yl)-134-oxadiazol-2-yl]-8-oxa-2-azaspiro[4.5]decan-2-yl}butan-1-one

SMILES

CC(C)CC(N(C1)CC2(CCOCC2)C1c1nnc(C(C)C)o1)=O

InChI

InChI=1S/C18H29N3O3/c1-12(2)9-15(22)21-10-14(17-20-19-16(24-17)13(3)4)18(11-21)5-7-23-8-6-18/h12-14H,5-11H2,1-4H3/t14-/m0/s1

InChI Key

ZCVDUJOPXUGGEV-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD29002493

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.411

Distribution Coefficient, logD

2.411

Water Solubility, LogSw

-2.15

Polar Surface Area

55.209

Acid Dissociation Constant (pKa)

24.55

Base Dissociation Constant (pKb)

-0.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

83.33

T655-0027 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with T655-0027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T655-0027?
Check Price and Availability of T655-0027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T655-0027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T655-0027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T655-0027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T655-0027 available by request