T865-1526 Screening compound: 3-phenyl-1-[3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one

T865-1526 Screening compound: 3-phenyl-1-[3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one
T865-1526 Screening compound: 3-phenyl-1-[3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T865-1526
3-phenyl-1-[3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T865-1526

Molecular Formula

C23H27N3O2 (C23 H27 N3 O2)

Compound Name

3-phenyl-1-[3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one

IUPAC name

3-phenyl-1-[(3R4S)-3-(pyridin-3-yl)-4-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propan-1-one

SMILES

O=C(CCc1ccccc1)N(C[C@@H]1C(N2CCCC2)=O)C[C@@H]1c1cnccc1

InChI

InChI=1S/C23H27N3O2/c27-22(11-10-18-7-2-1-3-8-18)26-16-20(19-9-6-12-24-15-19)21(17-26)23(28)25-13-4-5-14-25/h1-3,6-9,12,15,20-21H,4-5,10-11,13-14,16-17H2/t20-,21+/m1/s1

InChI Key

CGPVVZYTKJMOQV-RTWAWAEBSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.551

Distribution Coefficient, logD

2.551

Water Solubility, LogSw

-2.56

Polar Surface Area

42.853

Acid Dissociation Constant (pKa)

21.40

Base Dissociation Constant (pKb)

4.38

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

43.48

T865-1526 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with T865-1526 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T865-1526?
Check Price and Availability of T865-1526, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T865-1526 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T865-1526
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T865-1526
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T865-1526 available by request