V001-8992 Screening compound: 5'-chloro-N-(4-chlorophenyl)-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

V001-8992 Screening compound: 5'-chloro-N-(4-chlorophenyl)-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide
V001-8992 Screening compound: 5'-chloro-N-(4-chlorophenyl)-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V001-8992
5'-chloro-N-(4-chlorophenyl)-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V001-8992

Molecular Formula

C19H18Cl2N4O2 (C19 H18 Cl2 N4 O2)

Compound Name

5'-chloro-N-(4-chlorophenyl)-4'-oxo-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazoline]-1-carboxamide

IUPAC name

5'-chloro-N-(4-chlorophenyl)-4'-oxo-3'4'-dihydro-1'H-spiro[piperidine-42'-quinazoline]-1-carboxamide

SMILES

O=C(Nc(cc1)ccc1Cl)N(CC1)CCC1(Nc1cccc(Cl)c11)NC1=O

InChI

InChI=1S/C19H18Cl2N4O2/c20-12-4-6-13(7-5-12)22-18(27)25-10-8-19(9-11-25)23-15-3-1-2-14(21)16(15)17(26)24-19/h1-7,23H,8-11H2,(H,22,27)(H,24,26)

InChI Key

CUHINIVFADAZIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19939236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.491

Distribution Coefficient, logD

3.491

Water Solubility, LogSw

-4.29

Polar Surface Area

62.019

Acid Dissociation Constant (pKa)

12.23

Base Dissociation Constant (pKb)

1.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

V001-8992 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Anti-HIV1 Library (19540 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with V001-8992 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V001-8992?
Check Price and Availability of V001-8992, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V001-8992 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V001-8992
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V001-8992
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V001-8992 available by request