V002-9249 Screening compound: N-{4-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methoxybenzamide

V002-9249 Screening compound: N-{4-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methoxybenzamide
V002-9249 Screening compound: N-{4-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V002-9249
N-{4-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V002-9249

Molecular Formula

C23H18F2N2O3S (C23 H18 F2 N2 O3 S)

Compound Name

N-{4-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-4-methoxybenzamide

IUPAC name

N-{4-[3-(24-difluorophenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}-4-methoxybenzamide

SMILES

COc(cc1)ccc1C(Nc1ccc(C(N2c(ccc(F)c3)c3F)SCC2=O)cc1)=O

InChI

InChI=1S/C23H18F2N2O3S/c1-30-18-9-4-14(5-10-18)22(29)26-17-7-2-15(3-8-17)23-27(21(28)13-31-23)20-11-6-16(24)12-19(20)25/h2-12,23H,13H2,1H3,(H,26,29)/t23-/m0/s1

InChI Key

HWMNTXBSNIZBKR-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19861522

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.035

Distribution Coefficient, logD

4.035

Water Solubility, LogSw

-4.26

Polar Surface Area

46.467

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

-1.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

V002-9249 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V002-9249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V002-9249?
Check Price and Availability of V002-9249, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V002-9249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V002-9249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V002-9249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V002-9249 available by request