V003-2278 Screening compound: 2-{[5-(25-DIMETHOXYPHENYL)-12-OXAZOL-3-YL]FORMAMIDO}-3-METHYL-N-[(PYRIDIN-2-YL)METHYL]BUTANAMIDE

V003-2278 Screening compound: 2-{[5-(25-DIMETHOXYPHENYL)-12-OXAZOL-3-YL]FORMAMIDO}-3-METHYL-N-[(PYRIDIN-2-YL)METHYL]BUTANAMIDE
V003-2278 Screening compound: 2-{[5-(25-DIMETHOXYPHENYL)-12-OXAZOL-3-YL]FORMAMIDO}-3-METHYL-N-[(PYRIDIN-2-YL)METHYL]BUTANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound V003-2278
2-{[5-(25-DIMETHOXYPHENYL)-12-OXAZOL-3-YL]FORMAMIDO}-3-METHYL-N-[(PYRIDIN-2-YL)METHYL]BUTANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V003-2278

Molecular Formula

C23H26N4O5 (C23 H26 N4 O5)

Compound Name

2-{[5-(25-DIMETHOXYPHENYL)-12-OXAZOL-3-YL]FORMAMIDO}-3-METHYL-N-[(PYRIDIN-2-YL)METHYL]BUTANAMIDE

IUPAC name

2-{[5-(25-dimethoxyphenyl)-12-oxazol-3-yl]formamido}-3-methyl-N-[(pyridin-2-yl)methyl]butanamide

SMILES

CC(C)C(C(NCc1ncccc1)=O)NC(c1noc(-c(cc(cc2)OC)c2OC)c1)=O

InChI

InChI=1S/C23H26N4O5/c1-14(2)21(23(29)25-13-15-7-5-6-10-24-15)26-22(28)18-12-20(32-27-18)17-11-16(30-3)8-9-19(17)31-4/h5-12,14,21H,13H2,1-4H3,(H,25,29)(H,26,28)/t21-/m0/s1

InChI Key

QBAMSEYJRIQDBR-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19823309

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.517

Distribution Coefficient, logD

2.516

Water Solubility, LogSw

-2.97

Polar Surface Area

94.941

Acid Dissociation Constant (pKa)

12.67

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

V003-2278 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Endocrine
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with V003-2278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V003-2278?
Check Price and Availability of V003-2278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V003-2278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V003-2278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V003-2278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V003-2278 available by request