V004-6268 Screening compound: 3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-1,3-thiazolidine

V004-6268 Screening compound: 3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-1,3-thiazolidine
V004-6268 Screening compound: 3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-1,3-thiazolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V004-6268
3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-1,3-thiazolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V004-6268

Molecular Formula

C17H13F3N2O3S (C17 H13 F3 N2 O3 S)

Compound Name

3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-1,3-thiazolidine

IUPAC name

3-(3-nitrobenzoyl)-2-[2-(trifluoromethyl)phenyl]-13-thiazolidine

SMILES

[O-][N+](c1cccc(C(N2C(c3c(C(F)(F)F)cccc3)SCC2)=O)c1)=O

InChI

InChI=1S/C17H13F3N2O3S/c18-17(19,20)14-7-2-1-6-13(14)16-21(8-9-26-16)15(23)11-4-3-5-12(10-11)22(24)25/h1-7,10,16H,8-9H2/t16-/m0/s1

InChI Key

UXJFSXIDGUKMLX-INIZCTEOSA-N

MDL Number (MFCD)

MFCD19767333

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.36

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.109

Distribution Coefficient, logD

4.109

Water Solubility, LogSw

-4.39

Polar Surface Area

50.058

Acid Dissociation Constant (pKa)

26.15

Base Dissociation Constant (pKb)

-14.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.50

V004-6268 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V004-6268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V004-6268?
Check Price and Availability of V004-6268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V004-6268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V004-6268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V004-6268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V004-6268 available by request