V007-8344 Screening compound: 1-(2-chloro-6-fluorophenyl)-N-(2,4-difluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamide

V007-8344 Screening compound: 1-(2-chloro-6-fluorophenyl)-N-(2,4-difluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamide
V007-8344 Screening compound: 1-(2-chloro-6-fluorophenyl)-N-(2,4-difluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V007-8344
1-(2-chloro-6-fluorophenyl)-N-(2,4-difluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V007-8344

Molecular Formula

C24H20ClF3N2O3 (C24 H20 ClF3 N2 O3)

Compound Name

1-(2-chloro-6-fluorophenyl)-N-(2,4-difluorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamide

IUPAC name

1-(2-chloro-6-fluorophenyl)-N-(24-difluorophenyl)-67-dimethoxy-1234-tetrahydroisoquinoline-2-carboxamide

SMILES

COc1cc(CCN(C2c(c(F)ccc3)c3Cl)C(Nc(ccc(F)c3)c3F)=O)c2cc1OC

InChI

InChI=1S/C24H20ClF3N2O3/c1-32-20-10-13-8-9-30(24(31)29-19-7-6-14(26)11-18(19)28)23(15(13)12-21(20)33-2)22-16(25)4-3-5-17(22)27/h3-7,10-12,23H,8-9H2,1-2H3,(H,29,31)/t23-/m0/s1

InChI Key

FHNOBDRKNGGXIZ-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19958137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.073

Distribution Coefficient, logD

5.073

Water Solubility, LogSw

-5.48

Polar Surface Area

39.245

Acid Dissociation Constant (pKa)

11.13

Base Dissociation Constant (pKb)

-4.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.80

V007-8344 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V007-8344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V007-8344?
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What is the minimum amount of V007-8344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V007-8344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V007-8344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V007-8344 available by request