V008-1110 Screening compound: 3-(2-fluorophenyl)-6,7,8-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-one

V008-1110 Screening compound: 3-(2-fluorophenyl)-6,7,8-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-one
V008-1110 Screening compound: 3-(2-fluorophenyl)-6,7,8-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-1110
3-(2-fluorophenyl)-6,7,8-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-1110

Molecular Formula

C25H23FN2O4S (C25 H23 FN2 O4 S)

Compound Name

3-(2-fluorophenyl)-6,7,8-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-one

IUPAC name

3-(2-fluorophenyl)-678-trimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-34-dihydroquinazolin-4-one

SMILES

Cc1c(CSC(N(c(cccc2)c2F)C(c2cc(OC)c3OC)=O)=Nc2c3OC)cccc1

InChI

InChI=1S/C25H23FN2O4S/c1-15-9-5-6-10-16(15)14-33-25-27-21-17(13-20(30-2)22(31-3)23(21)32-4)24(29)28(25)19-12-8-7-11-18(19)26/h5-13H,14H2,1-4H3

InChI Key

ONDSHGZMRDHCTA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19858214

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.508

Distribution Coefficient, logD

5.507

Water Solubility, LogSw

-5.47

Polar Surface Area

45.671

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

4.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

V008-1110 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with V008-1110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-1110?
Check Price and Availability of V008-1110, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-1110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-1110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-1110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-1110 available by request