V008-1426 Screening compound: N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2,5-dimethylfuran-3-carboxamide

V008-1426 Screening compound: N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2,5-dimethylfuran-3-carboxamide
V008-1426 Screening compound: N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2,5-dimethylfuran-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-1426
N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2,5-dimethylfuran-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-1426

Molecular Formula

C22H18FN3O2 (C22 H18 FN3 O2)

Compound Name

N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-2,5-dimethylfuran-3-carboxamide

IUPAC name

N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-25-dimethylfuran-3-carboxamide

SMILES

Cc1cc(C(Nc2cc(-c3ccccc3)nn2-c2cccc(F)c2)=O)c(C)o1

InChI

InChI=1S/C22H18FN3O2/c1-14-11-19(15(2)28-14)22(27)24-21-13-20(16-7-4-3-5-8-16)25-26(21)18-10-6-9-17(23)12-18/h3-13H,1-2H3,(H,24,27)

InChI Key

HJWVVCHIOICZEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19976692

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.170

Distribution Coefficient, logD

5.170

Water Solubility, LogSw

-5.04

Polar Surface Area

45.240

Acid Dissociation Constant (pKa)

11.68

Base Dissociation Constant (pKb)

-4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

V008-1426 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

GPCR Targeted Library (31838 compounds)

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Others
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with V008-1426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-1426?
Check Price and Availability of V008-1426, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-1426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-1426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-1426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-1426 available by request