V008-1440 Screening compound: N~1~-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(4-pyridyl)propanamide

V008-1440 Screening compound: N~1~-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(4-pyridyl)propanamide
V008-1440 Screening compound: N~1~-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(4-pyridyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-1440
N~1~-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(4-pyridyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-1440

Molecular Formula

C23H19FN4O (C23 H19 FN4 O)

Compound Name

N~1~-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(4-pyridyl)propanamide

IUPAC name

N-[1-(3-fluorophenyl)-3-phenyl-1H-pyrazol-5-yl]-3-(pyridin-4-yl)propanamide

SMILES

O=C(CCc1ccncc1)Nc1cc(-c2ccccc2)nn1-c1cccc(F)c1

InChI

InChI=1S/C23H19FN4O/c24-19-7-4-8-20(15-19)28-22(16-21(27-28)18-5-2-1-3-6-18)26-23(29)10-9-17-11-13-25-14-12-17/h1-8,11-16H,9-10H2,(H,26,29)

InChI Key

NCBKISAYWHVXMI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19976723

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

386.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.161

Distribution Coefficient, logD

4.154

Water Solubility, LogSw

-4.34

Polar Surface Area

46.708

Acid Dissociation Constant (pKa)

11.96

Base Dissociation Constant (pKb)

5.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

V008-1440 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V008-1440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-1440?
Check Price and Availability of V008-1440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-1440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-1440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-1440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-1440 available by request