V008-2391 Screening compound: 5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine

V008-2391 Screening compound: 5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine
V008-2391 Screening compound: 5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-2391
5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-2391

Molecular Formula

C24H26ClFN4OS (C24 H26 ClFN4 OS)

Compound Name

5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine

IUPAC name

5-[(2-chloro-6-fluorophenyl)methyl]-2-methyl-4-(propan-2-yl)-6-[4-(thiophene-2-carbonyl)piperazin-1-yl]pyrimidine

SMILES

CC(C)c1nc(C)nc(N(CC2)CCN2C(c2cccs2)=O)c1Cc(c(F)ccc1)c1Cl

InChI

InChI=1S/C24H26ClFN4OS/c1-15(2)22-18(14-17-19(25)6-4-7-20(17)26)23(28-16(3)27-22)29-9-11-30(12-10-29)24(31)21-8-5-13-32-21/h4-8,13,15H,9-12,14H2,1-3H3

InChI Key

JCXHTCVBNUOYCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19788756

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

473.01

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.254

Distribution Coefficient, logD

6.209

Water Solubility, LogSw

-6.14

Polar Surface Area

39.781

Acid Dissociation Constant (pKa)

22.00

Base Dissociation Constant (pKb)

6.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

V008-2391 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V008-2391 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-2391?
Check Price and Availability of V008-2391, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-2391 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-2391
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-2391
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-2391 available by request