V008-6232 Screening compound: 2-(3,5-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H,2H,3H,4H,9H-pyrido[3,4-b]indole

V008-6232 Screening compound: 2-(3,5-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
V008-6232 Screening compound: 2-(3,5-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H,2H,3H,4H,9H-pyrido[3,4-b]indole alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-6232
2-(3,5-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H,2H,3H,4H,9H-pyrido[3,4-b]indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-6232

Molecular Formula

C26H20Cl2F2N2O3 (C26 H20 Cl2 F2 N2 O3)

Compound Name

2-(3,5-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H,2H,3H,4H,9H-pyrido[3,4-b]indole

IUPAC name

2-(35-dichlorobenzoyl)-1-[4-(difluoromethoxy)phenyl]-6-methoxy-1H2H3H4H9H-pyrido[34-b]indole

SMILES

COc(cc1)cc2c1[nH]c(C1c(cc3)ccc3OC(F)F)c2CCN1C(c1cc(Cl)cc(Cl)c1)=O

InChI

InChI=1S/C26H20Cl2F2N2O3/c1-34-19-6-7-22-21(13-19)20-8-9-32(25(33)15-10-16(27)12-17(28)11-15)24(23(20)31-22)14-2-4-18(5-3-14)35-26(29)30/h2-7,10-13,24,26,31H,8-9H2,1H3/t24-/m1/s1

InChI Key

RAKBQKSEYCARGM-XMMPIXPASA-N

MDL Number (MFCD)

MFCD19965880

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

517.36

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.773

Distribution Coefficient, logD

6.773

Water Solubility, LogSw

-6.50

Polar Surface Area

40.220

Acid Dissociation Constant (pKa)

18.39

Base Dissociation Constant (pKb)

-3.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

V008-6232 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V008-6232 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-6232?
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What is the minimum amount of V008-6232 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-6232
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-6232
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-6232 available by request