V008-6270 Screening compound: 1-{4-[4-(2H-1,3-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(2,3,4,5,6-pentafluorophenoxy)ethan-1-one

V008-6270 Screening compound: 1-{4-[4-(2H-1,3-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(2,3,4,5,6-pentafluorophenoxy)ethan-1-one
V008-6270 Screening compound: 1-{4-[4-(2H-1,3-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(2,3,4,5,6-pentafluorophenoxy)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-6270
1-{4-[4-(2H-1,3-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(2,3,4,5,6-pentafluorophenoxy)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-6270

Molecular Formula

C23H17F5N4O4 (C23 H17 F5 N4 O4)

Compound Name

1-{4-[4-(2H-1,3-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(2,3,4,5,6-pentafluorophenoxy)ethan-1-one

IUPAC name

1-{4-[4-(2H-13-benzodioxol-5-yl)pyrimidin-2-yl]piperazin-1-yl}-2-(23456-pentafluorophenoxy)ethan-1-one

SMILES

O=C(COc(c(F)c(c(F)c1F)F)c1F)N(CC1)CCN1c1nc(-c(cc2)cc3c2OCO3)ccn1

InChI

InChI=1S/C23H17F5N4O4/c24-17-18(25)20(27)22(21(28)19(17)26)34-10-16(33)31-5-7-32(8-6-31)23-29-4-3-13(30-23)12-1-2-14-15(9-12)36-11-35-14/h1-4,9H,5-8,10-11H2

InChI Key

FNYUYVMXPBMURH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19943808

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

508.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.209

Distribution Coefficient, logD

4.208

Water Solubility, LogSw

-4.40

Polar Surface Area

62.066

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

4.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

V008-6270 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V008-6270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-6270?
Check Price and Availability of V008-6270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-6270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-6270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-6270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-6270 available by request