V008-7217 Screening compound: 5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide

V008-7217 Screening compound: 5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide
V008-7217 Screening compound: 5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-7217
5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-7217

Molecular Formula

C28H25F3N4O2 (C28 H25 F3 N4 O2)

Compound Name

5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide

IUPAC name

5-cyclobutaneamido-N-[(pyridin-4-yl)methyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxamide

SMILES

O=C(C1CCC1)Nc(cc1)cc2c1n(Cc1ccc(C(F)(F)F)cc1)c(C(NCc1ccncc1)=O)c2

InChI

InChI=1S/C28H25F3N4O2/c29-28(30,31)22-6-4-19(5-7-22)17-35-24-9-8-23(34-26(36)20-2-1-3-20)14-21(24)15-25(35)27(37)33-16-18-10-12-32-13-11-18/h4-15,20H,1-3,16-17H2,(H,33,37)(H,34,36)

InChI Key

CAQNQPILOSGVSB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19784683

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

506.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.062

Distribution Coefficient, logD

4.059

Water Solubility, LogSw

-4.10

Polar Surface Area

58.148

Acid Dissociation Constant (pKa)

12.88

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

V008-7217 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V008-7217 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-7217?
Check Price and Availability of V008-7217, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-7217 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-7217
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-7217
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-7217 available by request