V008-8443 Screening compound: N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-1,4,8-triazaspiro[4.5]decane-8-carbothioamide

V008-8443 Screening compound: N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-1,4,8-triazaspiro[4.5]decane-8-carbothioamide
V008-8443 Screening compound: N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-1,4,8-triazaspiro[4.5]decane-8-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V008-8443
N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-1,4,8-triazaspiro[4.5]decane-8-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V008-8443

Molecular Formula

C23H35FN4OS (C23 H35 FN4 OS)

Compound Name

N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-1,4,8-triazaspiro[4.5]decane-8-carbothioamide

IUPAC name

N-(2-fluorophenyl)-1-(2-methylbutyl)-3-(2-methylpropyl)-2-oxo-148-triazaspiro[4.5]decane-8-carbothioamide

SMILES

CCC(C)CN(C(CC1)(CCN1C(Nc(cccc1)c1F)=S)NC1CC(C)C)C1=O

InChI

InChI=1S/C23H35FN4OS/c1-5-17(4)15-28-21(29)20(14-16(2)3)26-23(28)10-12-27(13-11-23)22(30)25-19-9-7-6-8-18(19)24/h6-9,16-17,20,26H,5,10-15H2,1-4H3,(H,25,30)

InChI Key

UBMXCRBZBMQDMQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19817973

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

434.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.941

Distribution Coefficient, logD

2.697

Water Solubility, LogSw

-4.37

Polar Surface Area

39.144

Acid Dissociation Constant (pKa)

13.18

Base Dissociation Constant (pKb)

9.64

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

65.20

V008-8443 in Drug Discovery

Included in Screening Libraries

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with V008-8443 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V008-8443?
Check Price and Availability of V008-8443, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V008-8443 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V008-8443
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V008-8443
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V008-8443 available by request