V010-0239 Screening compound: N-{3-[3-(3-fluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3,5-dimethoxybenzamide

V010-0239 Screening compound: N-{3-[3-(3-fluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3,5-dimethoxybenzamide
V010-0239 Screening compound: N-{3-[3-(3-fluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3,5-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V010-0239
N-{3-[3-(3-fluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3,5-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V010-0239

Molecular Formula

C24H21FN2O4S (C24 H21 FN2 O4 S)

Compound Name

N-{3-[3-(3-fluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3,5-dimethoxybenzamide

IUPAC name

N-{3-[3-(3-fluorophenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}-35-dimethoxybenzamide

SMILES

COc1cc(C(Nc2cccc(C(N3c4cc(F)ccc4)SCC3=O)c2)=O)cc(OC)c1

InChI

InChI=1S/C24H21FN2O4S/c1-30-20-10-16(11-21(13-20)31-2)23(29)26-18-7-3-5-15(9-18)24-27(22(28)14-32-24)19-8-4-6-17(25)12-19/h3-13,24H,14H2,1-2H3,(H,26,29)/t24-/m0/s1

InChI Key

KHXVTCSMXKLBPN-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD19860403

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.535

Distribution Coefficient, logD

4.535

Water Solubility, LogSw

-4.38

Polar Surface Area

54.312

Acid Dissociation Constant (pKa)

12.07

Base Dissociation Constant (pKb)

-0.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

V010-0239 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V010-0239 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V010-0239?
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What is the minimum amount of V010-0239 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V010-0239
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V010-0239
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V010-0239 available by request