V010-6949 Screening compound: 4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine

V010-6949 Screening compound: 4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine
V010-6949 Screening compound: 4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V010-6949
4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V010-6949

Molecular Formula

C22H20BrFN4O (C22 H20 BrFN4 O)

Compound Name

4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine

IUPAC name

4-[4-(3-bromobenzoyl)piperazin-1-yl]-2-(3-fluorophenyl)-6-methylpyrimidine

SMILES

Cc1cc(N(CC2)CCN2C(c2cccc(Br)c2)=O)nc(-c2cc(F)ccc2)n1

InChI

InChI=1S/C22H20BrFN4O/c1-15-12-20(26-21(25-15)16-4-3-7-19(24)14-16)27-8-10-28(11-9-27)22(29)17-5-2-6-18(23)13-17/h2-7,12-14H,8-11H2,1H3

InChI Key

ULWKZVVQMUCCKS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19851513

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

455.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.451

Distribution Coefficient, logD

5.438

Water Solubility, LogSw

-5.51

Polar Surface Area

37.717

Acid Dissociation Constant (pKa)

23.23

Base Dissociation Constant (pKb)

5.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

V010-6949 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Autophagy-Targeted Library (4564 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with V010-6949 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V010-6949?
Check Price and Availability of V010-6949, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V010-6949 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V010-6949
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V010-6949
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V010-6949 available by request