V010-7484 Screening compound: [8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]dec-3-yl](morpholino)methanone

V010-7484 Screening compound: [8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]dec-3-yl](morpholino)methanone
V010-7484 Screening compound: [8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]dec-3-yl](morpholino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V010-7484
[8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]dec-3-yl](morpholino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V010-7484

Molecular Formula

C26H26F3N3O5 (C26 H26 F3 N3 O5)

Compound Name

[8-(2,4-difluorobenzoyl)-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]dec-3-yl](morpholino)methanone

IUPAC name

8-(24-difluorobenzoyl)-4-(4-fluorobenzoyl)-3-(morpholine-4-carbonyl)-1-oxa-48-diazaspiro[4.5]decane

SMILES

O=C(C(COC1(CC2)CCN2C(c(ccc(F)c2)c2F)=O)N1C(c(cc1)ccc1F)=O)N1CCOCC1

InChI

InChI=1S/C26H26F3N3O5/c27-18-3-1-17(2-4-18)23(33)32-22(25(35)31-11-13-36-14-12-31)16-37-26(32)7-9-30(10-8-26)24(34)20-6-5-19(28)15-21(20)29/h1-6,15,22H,7-14,16H2/t22-/m1/s1

InChI Key

RPEDVQFXVSYTLB-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD19806440

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

517.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.799

Distribution Coefficient, logD

1.799

Water Solubility, LogSw

-2.45

Polar Surface Area

64.139

Acid Dissociation Constant (pKa)

20.29

Base Dissociation Constant (pKb)

-1.36

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.31

V010-7484 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Anti-HIV1 Library (19540 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with V010-7484 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V010-7484?
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What is the minimum amount of V010-7484 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V010-7484
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V010-7484
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V010-7484 available by request