V011-0857 Screening compound: 1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one

V011-0857 Screening compound: 1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one
V011-0857 Screening compound: 1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-0857
1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-0857

Molecular Formula

C25H23F3N2O (C25 H23 F3 N2 O)

Compound Name

1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one

IUPAC name

1-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-(4-fluorophenyl)ethan-1-one

SMILES

O=C(Cc(cc1)ccc1F)N(CC1)CCN1C(c(cc1)ccc1F)c(cc1)ccc1F

InChI

InChI=1S/C25H23F3N2O/c26-21-7-1-18(2-8-21)17-24(31)29-13-15-30(16-14-29)25(19-3-9-22(27)10-4-19)20-5-11-23(28)12-6-20/h1-12,25H,13-17H2

InChI Key

KDGUOFWVTUDFKB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19963188

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

424.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.720

Distribution Coefficient, logD

4.720

Water Solubility, LogSw

-4.77

Polar Surface Area

18.921

Acid Dissociation Constant (pKa)

17.74

Base Dissociation Constant (pKb)

4.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

V011-0857 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

DGK Inhibitors Library (10558 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with V011-0857 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-0857?
Check Price and Availability of V011-0857, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-0857 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-0857
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-0857
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-0857 available by request