V011-3265 Screening compound: 2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole-5-carboxylic acid

V011-3265 Screening compound: 2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole-5-carboxylic acid
V011-3265 Screening compound: 2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole-5-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-3265
2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole-5-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-3265

Molecular Formula

C25H19F4N3O3 (C25 H19 F4 N3 O3)

Compound Name

2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole-5-carboxylic acid

IUPAC name

2-{2-[(3-fluorophenyl)formamido]ethyl}-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-13-benzodiazole-5-carboxylic acid

SMILES

OC(c(cc1)cc2c1n(Cc1cc(C(F)(F)F)ccc1)c(CCNC(c1cccc(F)c1)=O)n2)=O

InChI

InChI=1S/C25H19F4N3O3/c26-19-6-2-4-16(12-19)23(33)30-10-9-22-31-20-13-17(24(34)35)7-8-21(20)32(22)14-15-3-1-5-18(11-15)25(27,28)29/h1-8,11-13H,9-10,14H2,(H,30,33)(H,34,35)

InChI Key

APSGWPUZSQNRKN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19801068

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

485.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.005

Distribution Coefficient, logD

2.807

Water Solubility, LogSw

-4.73

Polar Surface Area

63.806

Acid Dissociation Constant (pKa)

5.20

Base Dissociation Constant (pKb)

3.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

V011-3265 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

PI3K-Targeted Library (17255 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V011-3265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-3265?
Check Price and Availability of V011-3265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-3265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-3265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-3265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-3265 available by request