V011-8208 Screening compound: (2E)-N-[3-({[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide

V011-8208 Screening compound: (2E)-N-[3-({[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide
V011-8208 Screening compound: (2E)-N-[3-({[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-8208
(2E)-N-[3-({[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-8208

Molecular Formula

C32H27FN2O4 (C32 H27 FN2 O4)

Compound Name

(2E)-N-[3-({[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide

IUPAC name

(2E)-N-[3-({[(2H-13-benzodioxol-5-yl)methyl]carbamoyl}methyl)phenyl]-N-[(4-fluorophenyl)methyl]-3-phenylprop-2-enamide

SMILES

O=C(Cc1cccc(N(Cc(cc2)ccc2F)C(/C=C/c2ccccc2)=O)c1)NCc(cc1)cc2c1OCO2

InChI

InChI=1S/C32H27FN2O4/c33-27-13-9-24(10-14-27)21-35(32(37)16-12-23-5-2-1-3-6-23)28-8-4-7-25(17-28)19-31(36)34-20-26-11-15-29-30(18-26)39-22-38-29/h1-18H,19-22H2,(H,34,36)

InChI Key

CZYSRTPZFWHLJW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19915540

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

522.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.648

Distribution Coefficient, logD

5.648

Water Solubility, LogSw

-5.84

Polar Surface Area

56.377

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

-0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

V011-8208 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

MCL1 Targeted Library (12200 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with V011-8208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-8208?
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What is the minimum amount of V011-8208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-8208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-8208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-8208 available by request