V011-8249 Screening compound: N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide

V011-8249 Screening compound: N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide
V011-8249 Screening compound: N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V011-8249
N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V011-8249

Molecular Formula

C27H30FN5O2S (C27 H30 FN5 O2 S)

Compound Name

N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide

IUPAC name

N-cyclopropyl-3-[({4-[4-(2-fluorophenyl)piperazin-1-yl]-6-(methoxymethyl)pyrimidin-2-yl}sulfanyl)methyl]benzamide

SMILES

COCc1nc(SCc2cc(C(NC3CC3)=O)ccc2)nc(N(CC2)CCN2c(cccc2)c2F)c1

InChI

InChI=1S/C27H30FN5O2S/c1-35-17-22-16-25(33-13-11-32(12-14-33)24-8-3-2-7-23(24)28)31-27(30-22)36-18-19-5-4-6-20(15-19)26(34)29-21-9-10-21/h2-8,15-16,21H,9-14,17-18H2,1H3,(H,29,34)

InChI Key

WFAZRWCDDZBIEP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19834690

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

507.63

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.864

Distribution Coefficient, logD

4.864

Water Solubility, LogSw

-4.68

Polar Surface Area

56.524

Acid Dissociation Constant (pKa)

11.80

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

V011-8249 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V011-8249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V011-8249?
Check Price and Availability of V011-8249, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V011-8249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V011-8249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V011-8249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V011-8249 available by request