V012-0537 Screening compound: 4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide

V012-0537 Screening compound: 4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide
V012-0537 Screening compound: 4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V012-0537
4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V012-0537

Molecular Formula

C23H21FN2O4S2 (C23 H21 FN2 O4 S2)

Compound Name

4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide

IUPAC name

4-fluoro-N-{4-[3-(2-methoxy-5-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}benzene-1-sulfonamide

SMILES

Cc(cc1)cc(N(C(c(cc2)ccc2NS(c(cc2)ccc2F)(=O)=O)SC2)C2=O)c1OC

InChI

InChI=1S/C23H21FN2O4S2/c1-15-3-12-21(30-2)20(13-15)26-22(27)14-31-23(26)16-4-8-18(9-5-16)25-32(28,29)19-10-6-17(24)7-11-19/h3-13,23,25H,14H2,1-2H3/t23-/m0/s1

InChI Key

WCXQVPGSFTXDCJ-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19854866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.409

Distribution Coefficient, logD

4.353

Water Solubility, LogSw

-4.37

Polar Surface Area

64.112

Acid Dissociation Constant (pKa)

8.27

Base Dissociation Constant (pKb)

-9.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.40

V012-0537 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V012-0537 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V012-0537?
Check Price and Availability of V012-0537, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V012-0537 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V012-0537
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V012-0537
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V012-0537 available by request