V014-1269 Screening compound: N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

V014-1269 Screening compound: N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide
V014-1269 Screening compound: N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-1269
N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-1269

Molecular Formula

C21H17F3N4O3S (C21 H17 F3 N4 O3 S)

Compound Name

N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

IUPAC name

N-(2-{[2-(furan-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES

O=S(c1cc(C(F)(F)F)ccc1)(NCCNc1nc(-c2ccco2)nc2ccccc12)=O

InChI

InChI=1S/C21H17F3N4O3S/c22-21(23,24)14-5-3-6-15(13-14)32(29,30)26-11-10-25-19-16-7-1-2-8-17(16)27-20(28-19)18-9-4-12-31-18/h1-9,12-13,26H,10-11H2,(H,25,27,28)

InChI Key

OLWGWMFVKIYQCD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19780793

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

462.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.621

Distribution Coefficient, logD

4.618

Water Solubility, LogSw

-4.56

Polar Surface Area

79.419

Acid Dissociation Constant (pKa)

10.99

Base Dissociation Constant (pKb)

5.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

V014-1269 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with V014-1269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-1269?
Check Price and Availability of V014-1269, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-1269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-1269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-1269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-1269 available by request