V014-4881 Screening compound: 2-{[(2,4-DIMETHOXYPHENYL)CARBAMOYL]AMINO}-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)PENTANAMIDE

V014-4881 Screening compound: 2-{[(2,4-DIMETHOXYPHENYL)CARBAMOYL]AMINO}-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)PENTANAMIDE
V014-4881 Screening compound: 2-{[(2,4-DIMETHOXYPHENYL)CARBAMOYL]AMINO}-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)PENTANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-4881
2-{[(2,4-DIMETHOXYPHENYL)CARBAMOYL]AMINO}-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)PENTANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-4881

Molecular Formula

C23H27N5O4S (C23 H27 N5 O4 S)

Compound Name

2-{[(2,4-DIMETHOXYPHENYL)CARBAMOYL]AMINO}-3-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)PENTANAMIDE

IUPAC name

n/a

SMILES

CCC(C)C(C(Nc1nnc(-c2ccccc2)s1)=O)NC(Nc(ccc(OC)c1)c1OC)=O

InChI

InChI=1S/C23H27N5O4S/c1-5-14(2)19(25-22(30)24-17-12-11-16(31-3)13-18(17)32-4)20(29)26-23-28-27-21(33-23)15-9-7-6-8-10-15/h6-14,19H,5H2,1-4H3,(H2,24,25,30)(H,26,28,29)

InChI Key

WJTBCPPTIOYLRN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14242039

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.613

Distribution Coefficient, logD

4.613

Water Solubility, LogSw

-4.33

Polar Surface Area

94.328

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

3.40

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

30.40

V014-4881 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V014-4881 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-4881?
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What is the minimum amount of V014-4881 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-4881
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-4881
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-4881 available by request