V014-6263 Screening compound: 3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide

V014-6263 Screening compound: 3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide
V014-6263 Screening compound: 3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-6263
3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-6263

Molecular Formula

C28H27F3N2O (C28 H27 F3 N2 O)

Compound Name

3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide

IUPAC name

3-(7-ethyl-1H-indol-3-yl)-N-(1-phenylethyl)-3-[3-(trifluoromethyl)phenyl]propanamide

SMILES

CCc1cccc2c1[nH]cc2C(CC(NC(C)c1ccccc1)=O)c1cccc(C(F)(F)F)c1

InChI

InChI=1S/C28H27F3N2O/c1-3-19-11-8-14-23-25(17-32-27(19)23)24(21-12-7-13-22(15-21)28(29,30)31)16-26(34)33-18(2)20-9-5-4-6-10-20/h4-15,17-18,24,32H,3,16H2,1-2H3,(H,33,34)

InChI Key

YSPDXIBYAFGWDI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19850982

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.53

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.021

Distribution Coefficient, logD

7.021

Water Solubility, LogSw

-6.01

Polar Surface Area

33.971

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

-1.60

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

25.00

V014-6263 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Indole Derivatives (10091 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Nuclear receptors
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V014-6263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-6263?
Check Price and Availability of V014-6263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-6263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-6263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-6263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-6263 available by request