V014-6349 Screening compound: 2-methyl-N~1~-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazino}ethyl)-1H-indol-5-yl]butanamide

V014-6349 Screening compound: 2-methyl-N~1~-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazino}ethyl)-1H-indol-5-yl]butanamide
V014-6349 Screening compound: 2-methyl-N~1~-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazino}ethyl)-1H-indol-5-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-6349
2-methyl-N~1~-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazino}ethyl)-1H-indol-5-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-6349

Molecular Formula

C26H31F3N4O (C26 H31 F3 N4 O)

Compound Name

2-methyl-N~1~-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazino}ethyl)-1H-indol-5-yl]butanamide

IUPAC name

2-methyl-N-[3-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1H-indol-5-yl]butanamide

SMILES

CCC(C)C(Nc(cc1)cc2c1[nH]cc2CCN(CC1)CCN1c1cccc(C(F)(F)F)c1)=O

InChI

InChI=1S/C26H31F3N4O/c1-3-18(2)25(34)31-21-7-8-24-23(16-21)19(17-30-24)9-10-32-11-13-33(14-12-32)22-6-4-5-20(15-22)26(27,28)29/h4-8,15-18,30H,3,9-14H2,1-2H3,(H,31,34)/t18-/m0/s1

InChI Key

JJLWLQJCOSPWID-SFHVURJKSA-N

MDL Number (MFCD)

MFCD19943195

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

472.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.081

Distribution Coefficient, logD

4.882

Water Solubility, LogSw

-5.05

Polar Surface Area

40.443

Acid Dissociation Constant (pKa)

11.59

Base Dissociation Constant (pKb)

7.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

V014-6349 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with V014-6349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-6349?
Check Price and Availability of V014-6349, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-6349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-6349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-6349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-6349 available by request