V015-0125 Screening compound: N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

V015-0125 Screening compound: N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide
V015-0125 Screening compound: N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V015-0125
N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V015-0125

Molecular Formula

C21H16ClF3N4O2S2 (C21 H16 ClF3 N4 O2 S2)

Compound Name

N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

IUPAC name

N-(2-{[7-chloro-2-(thiophen-2-yl)quinazolin-4-yl]amino}ethyl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES

O=S(c1cc(C(F)(F)F)ccc1)(NCCNc1c(ccc(Cl)c2)c2nc(-c2cccs2)n1)=O

InChI

InChI=1S/C21H16ClF3N4O2S2/c22-14-6-7-16-17(12-14)28-20(18-5-2-10-32-18)29-19(16)26-8-9-27-33(30,31)15-4-1-3-13(11-15)21(23,24)25/h1-7,10-12,27H,8-9H2,(H,26,28,29)

InChI Key

SBKFYCJBWRSOGQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19780526

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

512.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.297

Distribution Coefficient, logD

6.290

Water Solubility, LogSw

-6.71

Polar Surface Area

71.859

Acid Dissociation Constant (pKa)

10.99

Base Dissociation Constant (pKb)

5.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.29

V015-0125 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Glucocorticoid receptors Library (4806 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Nuclear receptors
  • Others
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with V015-0125 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V015-0125?
Check Price and Availability of V015-0125, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V015-0125 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V015-0125
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V015-0125
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V015-0125 available by request