V015-4761 Screening compound: N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide

V015-4761 Screening compound: N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide
V015-4761 Screening compound: N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V015-4761
N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V015-4761

Molecular Formula

C24H21FN2O3S (C24 H21 FN2 O3 S)

Compound Name

N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide

IUPAC name

N-{4-[3-(2-fluoro-5-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}-2-phenoxyacetamide

SMILES

Cc(cc1)cc(N(C(c(cc2)ccc2NC(COc2ccccc2)=O)SC2)C2=O)c1F

InChI

InChI=1S/C24H21FN2O3S/c1-16-7-12-20(25)21(13-16)27-23(29)15-31-24(27)17-8-10-18(11-9-17)26-22(28)14-30-19-5-3-2-4-6-19/h2-13,24H,14-15H2,1H3,(H,26,28)/t24-/m0/s1

InChI Key

IEQVRTKVQIYMSA-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD19861381

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.714

Distribution Coefficient, logD

4.714

Water Solubility, LogSw

-4.44

Polar Surface Area

46.209

Acid Dissociation Constant (pKa)

12.54

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.67

V015-4761 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V015-4761 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V015-4761?
Check Price and Availability of V015-4761, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V015-4761 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V015-4761
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V015-4761
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V015-4761 available by request