V015-7365 Screening compound: 2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]sulfonyl}benzonitrile

V015-7365 Screening compound: 2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]sulfonyl}benzonitrile
V015-7365 Screening compound: 2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]sulfonyl}benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound V015-7365
2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]sulfonyl}benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V015-7365

Molecular Formula

C26H28N6O4S (C26 H28 N6 O4 S)

Compound Name

2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]sulfonyl}benzonitrile

IUPAC name

2-{[4-(4-methoxyphenoxy)-2-(4-methylpiperazin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-6-yl]sulfonyl}benzonitrile

SMILES

CN(CC1)CCN1c1nc(Oc(cc2)ccc2OC)c(CN(CC2)S(c(cccc3)c3C#N)(=O)=O)c2n1

InChI

InChI=1S/C26H28N6O4S/c1-30-13-15-31(16-14-30)26-28-23-11-12-32(37(33,34)24-6-4-3-5-19(24)17-27)18-22(23)25(29-26)36-21-9-7-20(35-2)8-10-21/h3-10H,11-16,18H2,1-2H3

InChI Key

VOZPJLBPOMWBQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908786

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

520.61

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.819

Distribution Coefficient, logD

3.247

Water Solubility, LogSw

-4.19

Polar Surface Area

89.645

Acid Dissociation Constant (pKa)

20.43

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

V015-7365 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with V015-7365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V015-7365?
Check Price and Availability of V015-7365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V015-7365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V015-7365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V015-7365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V015-7365 available by request