V016-6270 Screening compound: 3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-2,5-dihydro-1,2,4-triazin-5-one

V016-6270 Screening compound: 3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-2,5-dihydro-1,2,4-triazin-5-one
V016-6270 Screening compound: 3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-2,5-dihydro-1,2,4-triazin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V016-6270
3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-2,5-dihydro-1,2,4-triazin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V016-6270

Molecular Formula

C28H38N6O5 (C28 H38 N6 O5)

Compound Name

3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-2,5-dihydro-1,2,4-triazin-5-one

IUPAC name

3-[4-(cyclobutylmethoxy)-3-methoxyphenyl]-6-(3-oxo-3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-25-dihydro-124-triazin-5-one

SMILES

COc(cc(cc1)C(NN=C2CCC(N3CCN(CC(N4CCCC4)=O)CC3)=O)=NC2=O)c1OCC1CCC1

InChI

InChI=1S/C28H38N6O5/c1-38-24-17-21(7-9-23(24)39-19-20-5-4-6-20)27-29-28(37)22(30-31-27)8-10-25(35)34-15-13-32(14-16-34)18-26(36)33-11-2-3-12-33/h7,9,17,20H,2-6,8,10-16,18-19H2,1H3,(H,29,31,37)

InChI Key

MSNHNEKMEDWVCJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14264388

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

538.65

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

0.889

Distribution Coefficient, logD

0.889

Water Solubility, LogSw

-2.06

Polar Surface Area

98.467

Acid Dissociation Constant (pKa)

10.36

Base Dissociation Constant (pKb)

3.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.70

V016-6270 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V016-6270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V016-6270?
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What is the minimum amount of V016-6270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V016-6270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V016-6270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V016-6270 available by request