V018-1140 Screening compound: cyclopropyl[4-(2-isobutyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone

V018-1140 Screening compound: cyclopropyl[4-(2-isobutyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone
V018-1140 Screening compound: cyclopropyl[4-(2-isobutyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-1140
cyclopropyl[4-(2-isobutyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-1140

Molecular Formula

C23H32N4OS (C23 H32 N4 OS)

Compound Name

cyclopropyl[4-(2-isobutyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone

IUPAC name

3-(4-cyclopropanecarbonylpiperazin-1-yl)-5-(2-methylpropyl)-8-thia-46-diazatricyclo[7.5.0.0^{27}]tetradeca-1(9)2(7)35-tetraene

SMILES

CC(C)Cc1nc(N(CC2)CCN2C(C2CC2)=O)c(c(CCCCC2)c2s2)c2n1

InChI

InChI=1S/C23H32N4OS/c1-15(2)14-19-24-21(26-10-12-27(13-11-26)23(28)16-8-9-16)20-17-6-4-3-5-7-18(17)29-22(20)25-19/h15-16H,3-14H2,1-2H3

InChI Key

SYQFCWXPDZMATG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19852794

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

412.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.807

Distribution Coefficient, logD

5.224

Water Solubility, LogSw

-5.41

Polar Surface Area

41.521

Acid Dissociation Constant (pKa)

22.62

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

69.60

V018-1140 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V018-1140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-1140?
Check Price and Availability of V018-1140, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-1140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-1140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-1140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-1140 available by request