V018-1491 Screening compound: N-{2-(cyclopropylamino)-1-[1-(4-fluorobenzoyl)-4-piperidyl]-2-oxoethyl}-2-thiophenecarboxamide

V018-1491 Screening compound: N-{2-(cyclopropylamino)-1-[1-(4-fluorobenzoyl)-4-piperidyl]-2-oxoethyl}-2-thiophenecarboxamide
V018-1491 Screening compound: N-{2-(cyclopropylamino)-1-[1-(4-fluorobenzoyl)-4-piperidyl]-2-oxoethyl}-2-thiophenecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-1491
N-{2-(cyclopropylamino)-1-[1-(4-fluorobenzoyl)-4-piperidyl]-2-oxoethyl}-2-thiophenecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-1491

Molecular Formula

C22H24FN3O3S (C22 H24 FN3 O3 S)

Compound Name

N-{2-(cyclopropylamino)-1-[1-(4-fluorobenzoyl)-4-piperidyl]-2-oxoethyl}-2-thiophenecarboxamide

IUPAC name

N-cyclopropyl-2-[1-(4-fluorobenzoyl)piperidin-4-yl]-2-[(thiophen-2-yl)formamido]acetamide

SMILES

O=C(C(C(CC1)CCN1C(c(cc1)ccc1F)=O)NC(c1cccs1)=O)NC1CC1

InChI

InChI=1S/C22H24FN3O3S/c23-16-5-3-15(4-6-16)22(29)26-11-9-14(10-12-26)19(21(28)24-17-7-8-17)25-20(27)18-2-1-13-30-18/h1-6,13-14,17,19H,7-12H2,(H,24,28)(H,25,27)/t19-/m0/s1

InChI Key

LJGPWSLYANVBAD-IBGZPJMESA-N

MDL Number (MFCD)

MFCD19874443

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.697

Distribution Coefficient, logD

2.697

Water Solubility, LogSw

-2.97

Polar Surface Area

66.140

Acid Dissociation Constant (pKa)

12.84

Base Dissociation Constant (pKb)

1.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.91

V018-1491 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V018-1491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-1491?
Check Price and Availability of V018-1491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-1491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-1491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-1491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-1491 available by request