V018-2373 Screening compound: 6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-2,5-dione

V018-2373 Screening compound: 6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-2,5-dione
V018-2373 Screening compound: 6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-2,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-2373
6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-2,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-2373

Molecular Formula

C27H28N4O5 (C27 H28 N4 O5)

Compound Name

6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-2,5-dione

IUPAC name

6-[2-(morpholin-4-yl)-2-oxoethyl]-4-(3-phenoxyphenyl)-1-(prop-2-en-1-yl)-1H2H3H4H5H6H7H-pyrrolo[34-d]pyrimidine-25-dione

SMILES

C=CCN(C(CN1CC(N2CCOCC2)=O)=C(C(c2cc(Oc3ccccc3)ccc2)N2)C1=O)C2=O

InChI

InChI=1S/C27H28N4O5/c1-2-11-31-22-17-30(18-23(32)29-12-14-35-15-13-29)26(33)24(22)25(28-27(31)34)19-7-6-10-21(16-19)36-20-8-4-3-5-9-20/h2-10,16,25H,1,11-15,17-18H2,(H,28,34)/t25-/m0/s1

InChI Key

ACNYHLVRFWYSTM-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19801672

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.175

Distribution Coefficient, logD

2.169

Water Solubility, LogSw

-2.90

Polar Surface Area

75.764

Acid Dissociation Constant (pKa)

9.25

Base Dissociation Constant (pKb)

-1.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.60

V018-2373 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V018-2373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-2373?
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What is the minimum amount of V018-2373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-2373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-2373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-2373 available by request