V018-3617 Screening compound: 3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea

V018-3617 Screening compound: 3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea
V018-3617 Screening compound: 3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-3617
3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-3617

Molecular Formula

C23H24F3N5O (C23 H24 F3 N5 O)

Compound Name

3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea

IUPAC name

3-{5-amino-3-phenyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}-1-cyclohexylurea

SMILES

Nc(n(-c1ccc(C(F)(F)F)cc1)nc1-c2ccccc2)c1NC(NC1CCCCC1)=O

InChI

InChI=1S/C23H24F3N5O/c24-23(25,26)16-11-13-18(14-12-16)31-21(27)20(19(30-31)15-7-3-1-4-8-15)29-22(32)28-17-9-5-2-6-10-17/h1,3-4,7-8,11-14,17H,2,5-6,9-10,27H2,(H2,28,29,32)

InChI Key

FIIHOZGAOQVUMQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19846697

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

443.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.577

Distribution Coefficient, logD

4.577

Water Solubility, LogSw

-4.56

Polar Surface Area

65.784

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

-0.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

V018-3617 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with V018-3617 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-3617?
Check Price and Availability of V018-3617, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-3617 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-3617
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-3617
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-3617 available by request