V018-7203 Screening compound: N-{4-[3-(2,3-dihydro-1H-inden-5-yl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3-methylbutanamide

V018-7203 Screening compound: N-{4-[3-(2,3-dihydro-1H-inden-5-yl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3-methylbutanamide
V018-7203 Screening compound: N-{4-[3-(2,3-dihydro-1H-inden-5-yl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3-methylbutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-7203
N-{4-[3-(2,3-dihydro-1H-inden-5-yl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3-methylbutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-7203

Molecular Formula

C23H26N2O2S (C23 H26 N2 O2 S)

Compound Name

N-{4-[3-(2,3-dihydro-1H-inden-5-yl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}-3-methylbutanamide

IUPAC name

N-{4-[3-(23-dihydro-1H-inden-5-yl)-4-oxo-13-thiazolidin-2-yl]phenyl}-3-methylbutanamide

SMILES

CC(C)CC(Nc1ccc(C(N2c3cc(CCC4)c4cc3)SCC2=O)cc1)=O

InChI

InChI=1S/C23H26N2O2S/c1-15(2)12-21(26)24-19-9-6-17(7-10-19)23-25(22(27)14-28-23)20-11-8-16-4-3-5-18(16)13-20/h6-11,13,15,23H,3-5,12,14H2,1-2H3,(H,24,26)/t23-/m0/s1

InChI Key

ROPXBMLWOBBMOB-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19858530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.728

Distribution Coefficient, logD

4.728

Water Solubility, LogSw

-4.48

Polar Surface Area

39.569

Acid Dissociation Constant (pKa)

12.21

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

V018-7203 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V018-7203 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-7203?
Check Price and Availability of V018-7203, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-7203 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-7203
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-7203
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-7203 available by request