V021-0677 Screening compound: N-benzyl-6-(2,6-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

V021-0677 Screening compound: N-benzyl-6-(2,6-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine
V021-0677 Screening compound: N-benzyl-6-(2,6-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-0677
N-benzyl-6-(2,6-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-0677

Molecular Formula

C28H23F3N4O2 (C28 H23 F3 N4 O2)

Compound Name

N-benzyl-6-(2,6-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

IUPAC name

N-benzyl-6-(26-difluorobenzoyl)-4-(2-fluorophenoxy)-N-methyl-5H6H7H8H-pyrido[43-d]pyrimidin-2-amine

SMILES

CN(Cc1ccccc1)c1nc(Oc(cccc2)c2F)c(CN(CC2)C(c(c(F)ccc3)c3F)=O)c2n1

InChI

InChI=1S/C28H23F3N4O2/c1-34(16-18-8-3-2-4-9-18)28-32-23-14-15-35(27(36)25-21(30)11-7-12-22(25)31)17-19(23)26(33-28)37-24-13-6-5-10-20(24)29/h2-13H,14-17H2,1H3

InChI Key

SGUQXZZSKLKYTA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19934254

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

504.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.705

Distribution Coefficient, logD

5.705

Water Solubility, LogSw

-5.66

Polar Surface Area

46.094

Acid Dissociation Constant (pKa)

19.30

Base Dissociation Constant (pKb)

1.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.86

V021-0677 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V021-0677 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-0677?
Check Price and Availability of V021-0677, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-0677 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-0677
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-0677
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-0677 available by request