V021-3281 Screening compound: 1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V021-3281 Screening compound: 1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V021-3281 Screening compound: 1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-3281
1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-3281

Molecular Formula

C21H20FN3O2S (C21 H20 FN3 O2 S)

Compound Name

1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-benzyl-5-fluoro-2-oxo-N-(prop-2-en-1-yl)-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

C=CCNC(N1C(c(cc(cc2)F)c2N2Cc3ccccc3)(C2=O)SCC1)=O

InChI

InChI=1S/C21H20FN3O2S/c1-2-10-23-20(27)25-11-12-28-21(25)17-13-16(22)8-9-18(17)24(19(21)26)14-15-6-4-3-5-7-15/h2-9,13H,1,10-12,14H2,(H,23,27)/t21-/m0/s1

InChI Key

JZAJFTOTWVKNCE-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19871505

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.721

Distribution Coefficient, logD

3.721

Water Solubility, LogSw

-4.03

Polar Surface Area

41.835

Acid Dissociation Constant (pKa)

15.67

Base Dissociation Constant (pKb)

-1.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

V021-3281 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V021-3281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-3281?
Check Price and Availability of V021-3281, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-3281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-3281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-3281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-3281 available by request