V021-8188 Screening compound: 1-METHYL-4-[6-(2-METHYLBENZOYL)-4-(4-METHYLPHENOXY)-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL]PIPERAZINE

V021-8188 Screening compound: 1-METHYL-4-[6-(2-METHYLBENZOYL)-4-(4-METHYLPHENOXY)-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL]PIPERAZINE
V021-8188 Screening compound: 1-METHYL-4-[6-(2-METHYLBENZOYL)-4-(4-METHYLPHENOXY)-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL]PIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-8188
1-METHYL-4-[6-(2-METHYLBENZOYL)-4-(4-METHYLPHENOXY)-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL]PIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-8188

Molecular Formula

C27H31N5O2 (C27 H31 N5 O2)

Compound Name

1-METHYL-4-[6-(2-METHYLBENZOYL)-4-(4-METHYLPHENOXY)-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL]PIPERAZINE

IUPAC name

1-methyl-4-[6-(2-methylbenzoyl)-4-(4-methylphenoxy)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]piperazine

SMILES

Cc(cc1)ccc1Oc1c(CN(CC2)C(c3c(C)cccc3)=O)c2nc(N2CCN(C)CC2)n1

InChI

InChI=1S/C27H31N5O2/c1-19-8-10-21(11-9-19)34-25-23-18-32(26(33)22-7-5-4-6-20(22)2)13-12-24(23)28-27(29-25)31-16-14-30(3)15-17-31/h4-11H,12-18H2,1-3H3

InChI Key

VVFKFVLXXLSVSU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908407

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.567

Distribution Coefficient, logD

3.995

Water Solubility, LogSw

-4.48

Polar Surface Area

49.982

Acid Dissociation Constant (pKa)

20.15

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

V021-8188 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with V021-8188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-8188?
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What is the minimum amount of V021-8188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-8188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-8188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-8188 available by request