V021-8765 Screening compound: 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide

V021-8765 Screening compound: 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide
V021-8765 Screening compound: 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-8765
3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-8765

Molecular Formula

C21H24ClN3O (C21 H24 ClN3 O)

Compound Name

3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide

IUPAC name

3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-N-cyclopropylbenzamide

SMILES

O=C(c1cccc(CN(CC2)CCN2c(cc2)ccc2Cl)c1)NC1CC1

InChI

InChI=1S/C21H24ClN3O/c22-18-4-8-20(9-5-18)25-12-10-24(11-13-25)15-16-2-1-3-17(14-16)21(26)23-19-6-7-19/h1-5,8-9,14,19H,6-7,10-13,15H2,(H,23,26)

InChI Key

VYEDMCHOKMVUEP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19914359

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

369.89

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.436

Distribution Coefficient, logD

3.404

Water Solubility, LogSw

-3.89

Polar Surface Area

31.701

Acid Dissociation Constant (pKa)

11.65

Base Dissociation Constant (pKb)

6.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

V021-8765 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V021-8765 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-8765?
Check Price and Availability of V021-8765, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-8765 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-8765
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-8765
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-8765 available by request