V022-0081 Screening compound: 1-ethyl-5',5'-dimethyl-2-oxo-N-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V022-0081 Screening compound: 1-ethyl-5',5'-dimethyl-2-oxo-N-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V022-0081 Screening compound: 1-ethyl-5',5'-dimethyl-2-oxo-N-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-0081
1-ethyl-5',5'-dimethyl-2-oxo-N-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-0081

Molecular Formula

C21H23N3O2S (C21 H23 N3 O2 S)

Compound Name

1-ethyl-5',5'-dimethyl-2-oxo-N-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-ethyl-5'5'-dimethyl-2-oxo-N-phenyl-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

CCN(C(C12SC(C)(C)CN1C(Nc1ccccc1)=O)=O)c1c2cccc1

InChI

InChI=1S/C21H23N3O2S/c1-4-23-17-13-9-8-12-16(17)21(18(23)25)24(14-20(2,3)27-21)19(26)22-15-10-6-5-7-11-15/h5-13H,4,14H2,1-3H3,(H,22,26)/t21-/m0/s1

InChI Key

LXTXCUAEWDXXCI-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19870163

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.434

Distribution Coefficient, logD

4.434

Water Solubility, LogSw

-4.30

Polar Surface Area

40.330

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

V022-0081 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic
  • PPI modulators
  • PPI modulators
Targets:
  • Others
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V022-0081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-0081?
Check Price and Availability of V022-0081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V022-0081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-0081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-0081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-0081 available by request