V022-0148 Screening compound: N6-(cyclopropylmethyl)-4-(2,5-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

V022-0148 Screening compound: N6-(cyclopropylmethyl)-4-(2,5-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
V022-0148 Screening compound: N6-(cyclopropylmethyl)-4-(2,5-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-0148
N6-(cyclopropylmethyl)-4-(2,5-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-0148

Molecular Formula

C22H20F2N6 (C22 H20 F2 N6)

Compound Name

N6-(cyclopropylmethyl)-4-(2,5-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

IUPAC name

N6-(cyclopropylmethyl)-4-(25-difluorophenyl)-2-(3-methylphenyl)-2H-pyrazolo[34-d]pyrimidine-36-diamine

SMILES

Cc1cccc(-n(c(N)c23)nc3nc(NCC3CC3)nc2-c(cc(cc2)F)c2F)c1

InChI

InChI=1S/C22H20F2N6/c1-12-3-2-4-15(9-12)30-20(25)18-19(16-10-14(23)7-8-17(16)24)27-22(28-21(18)29-30)26-11-13-5-6-13/h2-4,7-10,13H,5-6,11,25H2,1H3,(H,26,28,29)

InChI Key

FOIDAPSPZBVRNA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14250113

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

406.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.290

Distribution Coefficient, logD

5.290

Water Solubility, LogSw

-5.82

Polar Surface Area

65.334

Acid Dissociation Constant (pKa)

19.03

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

V022-0148 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V022-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-0148?
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What is the minimum amount of V022-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-0148 available by request