V022-0435 Screening compound: N-{3-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide

V022-0435 Screening compound: N-{3-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide
V022-0435 Screening compound: N-{3-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-0435
N-{3-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-0435

Molecular Formula

C20H20N2O2S (C20 H20 N2 O2 S)

Compound Name

N-{3-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide

IUPAC name

N-{3-[3-(4-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}cyclopropanecarboxamide

SMILES

Cc(cc1)ccc1N(C(c1cc(NC(C2CC2)=O)ccc1)SC1)C1=O

InChI

InChI=1S/C20H20N2O2S/c1-13-5-9-17(10-6-13)22-18(23)12-25-20(22)15-3-2-4-16(11-15)21-19(24)14-7-8-14/h2-6,9-11,14,20H,7-8,12H2,1H3,(H,21,24)/t20-/m0/s1

InChI Key

HJUUVSTWWVRFAT-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD19855329

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.786

Distribution Coefficient, logD

3.786

Water Solubility, LogSw

-3.81

Polar Surface Area

39.747

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

4.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

V022-0435 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V022-0435 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-0435?
Check Price and Availability of V022-0435, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V022-0435 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-0435
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-0435
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-0435 available by request