V022-0504 Screening compound: N-{4-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

V022-0504 Screening compound: N-{4-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide
V022-0504 Screening compound: N-{4-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-0504
N-{4-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-0504

Molecular Formula

C21H22N2O3S (C21 H22 N2 O3 S)

Compound Name

N-{4-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

IUPAC name

N-{4-[3-(4-methoxyphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

SMILES

COc(cc1)ccc1N(C(c(cc1)ccc1NC(C1CCC1)=O)SC1)C1=O

InChI

InChI=1S/C21H22N2O3S/c1-26-18-11-9-17(10-12-18)23-19(24)13-27-21(23)15-5-7-16(8-6-15)22-20(25)14-3-2-4-14/h5-12,14,21H,2-4,13H2,1H3,(H,22,25)/t21-/m0/s1

InChI Key

ZRPOXJCFVUBYMV-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19855389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.703

Distribution Coefficient, logD

2.703

Water Solubility, LogSw

-3.22

Polar Surface Area

47.291

Acid Dissociation Constant (pKa)

12.15

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

V022-0504 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V022-0504 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-0504?
Check Price and Availability of V022-0504, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V022-0504 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-0504
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-0504
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-0504 available by request