V022-7646 Screening compound: 4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

V022-7646 Screening compound: 4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
V022-7646 Screening compound: 4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-7646
4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-7646

Molecular Formula

C22H19Cl2FN6 (C22 H19 Cl2 FN6)

Compound Name

4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

IUPAC name

4-(3-chloro-4-fluorophenyl)-2-(2-chlorophenyl)-N6-cyclopentyl-2H-pyrazolo[34-d]pyrimidine-36-diamine

SMILES

Nc1c2c(-c(cc3)cc(Cl)c3F)nc(NC3CCCC3)nc2nn1-c(cccc1)c1Cl

InChI

InChI=1S/C22H19Cl2FN6/c23-14-7-3-4-8-17(14)31-20(26)18-19(12-9-10-16(25)15(24)11-12)28-22(29-21(18)30-31)27-13-5-1-2-6-13/h3-4,7-11,13H,1-2,5-6,26H2,(H,27,29,30)

InChI Key

VXYGLFBVFCUNIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14250017

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

457.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.870

Distribution Coefficient, logD

5.869

Water Solubility, LogSw

-6.29

Polar Surface Area

64.601

Acid Dissociation Constant (pKa)

16.87

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

V022-7646 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V022-7646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-7646?
Check Price and Availability of V022-7646, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V022-7646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-7646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-7646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-7646 available by request