V024-3312 Screening compound: 7'-chloro-1-[(4-fluorophenyl)sulfonyl]-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

V024-3312 Screening compound: 7'-chloro-1-[(4-fluorophenyl)sulfonyl]-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one
V024-3312 Screening compound: 7'-chloro-1-[(4-fluorophenyl)sulfonyl]-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V024-3312
7'-chloro-1-[(4-fluorophenyl)sulfonyl]-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V024-3312

Molecular Formula

C18H17ClFN3O3S (C18 H17 ClFN3 O3 S)

Compound Name

7'-chloro-1-[(4-fluorophenyl)sulfonyl]-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

IUPAC name

7'-chloro-1-(4-fluorobenzenesulfonyl)-3'4'-dihydro-1'H-spiro[piperidine-42'-quinazolin]-4'-one

SMILES

O=C1NC(CC2)(CCN2S(c(cc2)ccc2F)(=O)=O)Nc2c1ccc(Cl)c2

InChI

InChI=1S/C18H17ClFN3O3S/c19-12-1-6-15-16(11-12)21-18(22-17(15)24)7-9-23(10-8-18)27(25,26)14-4-2-13(20)3-5-14/h1-6,11,21H,7-10H2,(H,22,24)

InChI Key

RPXIWYUIHWFJJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19939245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.87

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.884

Distribution Coefficient, logD

2.884

Water Solubility, LogSw

-3.77

Polar Surface Area

68.261

Acid Dissociation Constant (pKa)

13.24

Base Dissociation Constant (pKb)

5.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

V024-3312 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V024-3312 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V024-3312?
Check Price and Availability of V024-3312, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V024-3312 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V024-3312
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V024-3312
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V024-3312 available by request