V025-0615 Screening compound: 1-benzyl-5'-chloro-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-one

V025-0615 Screening compound: 1-benzyl-5'-chloro-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-one
V025-0615 Screening compound: 1-benzyl-5'-chloro-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V025-0615
1-benzyl-5'-chloro-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V025-0615

Molecular Formula

C19H20ClN3O (C19 H20 ClN3 O)

Compound Name

1-benzyl-5'-chloro-3',4'-dihydro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-one

IUPAC name

1-benzyl-5'-chloro-3'4'-dihydro-1'H-spiro[piperidine-42'-quinazolin]-4'-one

SMILES

O=C1NC2(CCN(Cc3ccccc3)CC2)Nc2cccc(Cl)c12

InChI

InChI=1S/C19H20ClN3O/c20-15-7-4-8-16-17(15)18(24)22-19(21-16)9-11-23(12-10-19)13-14-5-2-1-3-6-14/h1-8,21H,9-13H2,(H,22,24)

InChI Key

JONHGHBKAJKZFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19939330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.325

Distribution Coefficient, logD

2.911

Water Solubility, LogSw

-3.96

Polar Surface Area

40.282

Acid Dissociation Constant (pKa)

13.24

Base Dissociation Constant (pKb)

7.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.58

V025-0615 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with V025-0615 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V025-0615?
Check Price and Availability of V025-0615, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V025-0615 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V025-0615
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V025-0615
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V025-0615 available by request