V027-8145 Screening compound: 1-(3,4-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]urea

V027-8145 Screening compound: 1-(3,4-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]urea
V027-8145 Screening compound: 1-(3,4-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound V027-8145
1-(3,4-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V027-8145

Molecular Formula

C21H16F2N4O2 (C21 H16 F2 N4 O2)

Compound Name

1-(3,4-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]urea

IUPAC name

1-(34-difluorophenyl)-3-[2-(3-methoxyphenyl)imidazo[12-a]pyridin-3-yl]urea

SMILES

COc1cccc(-c2c(NC(Nc(cc3)cc(F)c3F)=O)n(cccc3)c3n2)c1

InChI

InChI=1S/C21H16F2N4O2/c1-29-15-6-4-5-13(11-15)19-20(27-10-3-2-7-18(27)25-19)26-21(28)24-14-8-9-16(22)17(23)12-14/h2-12H,1H3,(H2,24,26,28)

InChI Key

NGIFFPOVTAKGBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19971118

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

394.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.841

Distribution Coefficient, logD

4.840

Water Solubility, LogSw

-4.63

Polar Surface Area

48.613

Acid Dissociation Constant (pKa)

10.58

Base Dissociation Constant (pKb)

4.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

V027-8145 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Others
  • Ion Channels

References: we are preparing a list of scientific research reports with V027-8145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V027-8145?
Check Price and Availability of V027-8145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V027-8145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V027-8145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V027-8145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V027-8145 available by request